Galaxy FastQC exome processing time

Post author
Nicolas LeBlanc

I am attempting to run a FastQC in Galaxy on a paired Fastq exome file (3-4gb .gz each). I launched the VM with 32 CPUs and 120gb of ram. My file has now been running for 22 hours.

I wanted to know if this is a normal time or if there is a setting I can optimize. My end goal after the FastQC analysis is to do a variant calling and the adapters have already been removed from the file from the genetics company.

I had success in Terra in turning the same fastq files into ubam and gvcf (I opened the gvcf in IGV) so I don't believe the fastq files are an issue.

Lastly this is my 2nd attempt as my first attempt with 2 cpus and 32gb of ram ran for 24h and the first pair of outputs still did not process so I cancelled the job and now running it in a new workspace.

Any insight that can be provided would be appreciated.

Comments

1 comment

  • Comment author
    Emily Barnes

    Hi Nicolas,

    Just to confirm, are you running this on one 3-4 GB file, or are you working with multiple files at once? Are the files located in a workspace in Terra? If so would you be able to share this workspace with support by clicking the Share button in your workspace? The Share option is in the three-dots menu at the top-right.

    1. Toggle the "Share with support" button to "Yes"
    2. Click Save

     

    Please provide us with a link to your workspace and the name of the file. We’ll be happy to take a closer look as soon as we can!

     

    Best,
    Emily

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